Publications – Infection

Publications – Infection

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Clin. Microbiol. Infect., 2015

Weiss, E ; Zahar, JR ; Lesprit, P ; Ruppe, E ; Leone, M ; Chastre, J & al
Elaboration of a consensual definition of de-escalation allowing a ranking of β-lactams.


Crit Care., 2014

Brun-Buisson, C
Minimizing antibiotic exposure in the ICU: in search of the optimal strategy.


Eur. J. Clin. Microbiol. Infect. Dis., 2013

Delory, T ; De Pontfarcy, A ; Emirian, A ; About, F ; Berdougo, B ; Brun-Buisson, C & al
Impact of a program combining pre-authorization requirement and post-prescription review of carbapenems: an interrupted time-series analysis.


Ann Intensive Care, 2013

Dupuy, AM ; Philippart, F ; Péan, Y ; Lasocki, S ; Charles, PE ; Chalumeau, M & al
Role of biomarkers in the management of antibiotic therapy: an expert panel review: I – currently available biomarkers for clinical use in acute infections.


Ann Intensive Care, 2013

Quenot, JP ; Luyt, CE ; Roche, N ; Chalumeau, M ; Charles, PE ; Claessens, YE & al
Role of biomarkers in the management of antibiotic therapy: an expert panel review II: clinical use of biomarkers for initiation or discontinuation of antibiotic therapy.


Clin. Microbiol. Infect., 2013

Lesprit, P ; Landelle, C ; Brun-Buisson, C
Clinical impact of unsolicited post-prescription antibiotic review in surgical and medical wards: a randomized controlled trial.


Eur. J. Clin. Microbiol. Infect. Dis., 2013

Lesprit, P ; Landelle, C ; Brun-Buisson, C
Unsolicited post-prescription antibiotic review in surgical and medical wards: factors associated with counselling and physicians’ compliance.


Crit Care., 2014

Tabah, A ; Koulenti, D ; Laupland, K ; Misset, B ; Valles, J ; Bruzzi de Carvalho, F & al
Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study.


Presse Med, 2011

Lesprit, P ; Merabet, L ; Fernandez, J ; Legrand, P ; Brun-Buisson, C
Improving antibiotic use in the hospital: Focusing on positive blood cultures is an effective option.


Lancet, 2010

Bouadma, L ; Luyt, CE ; Tubach, F ; Cracco, C ; Alvarez, A ; Schwebel, C & al
Use of procalcitonin to reduce patients’ exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.


J. Antimicrob. Chemother., 2010

Lesprit, P ; Landelle, C ; Girou, E ; Brun-Buisson, C,

Reassessment of intravenous antibiotic therapy using a reminder or direct counselling.


J. Antimicrob. Chemother., 2009

Lesprit, P ; Duong, T ; Girou, E ; Hemery, F ; Brun-Buisson, C,

Impact of a computer-generated alert system prompting review of antibiotic use in hospitals.


Curr. Opin. Infect. Dis., 2008

Lesprit, P ; Brun-Buisson, C
Hospital antibiotic stewardship.


Intensive Care Med, 2007

Aarts, MA ; Brun-Buisson, C ; Cook, DJ ; Kumar, A ; Opal, S ; Rocker, G & al
Antibiotic management of suspected nosocomial ICU-acquired infection: does prolonged empiric therapy improve outcome?


Intensive Care Med, 2007

Aarts, MA ; Brun-Buisson, C ; Cook, DJ ; Kumar, A ; Opal, S ; Rocker, G & al
Antibiotic management of suspected nosocomial ICU-acquired infection: does prolonged empiric therapy improve outcome?


J. Antimicrob. Chemother., 2006

Zahar, JR ; Rioux, C ; Girou, E ; Hulin, A ; Sauve, C ; Bernier-Combes, A & al
Inappropriate prescribing of aminoglycosides: risk factors and impact of an antibiotic control team.


Chest, 2003

Brun-Buisson, C
Antibiotic therapy of ventilator-associated pneumonia: in search of the magic bullet.


Semin Respir Crit Care Med, 2002

Brun-Buisson, C
Guidelines for treatment of hospital-acquired pneumonia.


Emerging Infect. Dis., 2002

Harbarth, S ; Albrich, W ; Brun-Buisson, C
Outpatient antibiotic use and prevalence of antibiotic-resistant pneumococci in France and Germany: a sociocultural perspective.


Clin. Microbiol. Infect., 2001

Andremont, A ; Brun-Buisson, C ; Struelens, M
Evaluating and predicting the ecologic impact of antibiotics.


J. Antimicrob. Chemother., 2000

Thuong, M ; Shortgen, F ; Zazempa, V ; Girou, E ; Soussy, CJ ; Brun-Buisson, C
Appropriate use of restricted antimicrobial agents in hospitals: the importance of empirical therapy and assisted re-evaluation.


Clin. Infect. Dis., 1998

Brun-Buisson, C ; Sollet, JP ; Schweich, H ; Brière, S ; Petit, C
Treatment of ventilator-associated pneumonia with piperacillin-tazobactam/amikacin versus ceftazidime/amikacin: a multicenter, randomized controlled trial. VAP Study Group.


Clin. Infect. Dis., 1997

Aubry-Damon, H ; Legrand, P ; Brun-Buisson, C ; Astier, A ; Soussy, CJ ; Leclercq, R
Reemergence of gentamicin-susceptible strains of methicillin-resistant Staphylococcus aureus: roles of an infection control program and changes in aminoglycoside use.


Lancet, 1987

Brun-Buisson, C; Legrand, P; Philippon, A; Montravers, F; Ansquer, M; Duval, J.
Transferable enzymatic resistance to third generation cephalosporins during nosocomial outbreak of multiple-resistant Klebsiella pneumoniae.


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Intensive Care Med, 2004

Brun-Buisson, C
Suspected central venous catheter-associated infection: can the catheter be safely retained?


Intensive Care Med, 2004

Brun-Buisson, C ; Doyon, F ; Sollet, JP ; Cochard, JF ; Cohen, Y ; Nitenberg, G
Prevention of intravascular catheter-related infection with newer chlorhexidine-silver sulfadiazine-coated catheters: a randomized controlled trial.


Am. J. Respir. Crit. Care Med., 2001

Brun-Buisson, C
New technologies and infection control practices to prevent intravascular catheter-related infections.


Am. J. Respir. Crit. Care Med., 2001

Renaud, B ; Brun-Buisson, C
Outcomes of primary and catheter-related bacteremia. A cohort and case-control study in critically ill patients.


Support Care Cancer, 2000

Blot, F ; Nitenberg, G ; Brun-Buisson, C
New tools in diagnosing catheter-related infections.


Lancet, 1999

Blot, F ; Nitenberg, G ; Chachaty, E ; Raynard, B ; Germann, N ; Antoun, S & al
Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures.


Crit. Care Med., 1998

Randolph, AG ; Cook, DJ ; Gonzales, CA ; Brun-Buisson, C
Tunneling short-term central venous catheters to prevent catheter-related infection: a meta-analysis of randomized, controlled trials.


Crit. Care Med., 1997

Cook, D ; Randolph, A ; Kernerman, P ; Cupido, C ; King, D ; Soukup, C & al
Central venous catheter replacement strategies: a systematic review of the literature.


Infect Control Hosp Epidemiol, 1997

Durand-Zaleski, I ; Delaunay, L ; Langeron, O ; Belda, E ; Astier, A ; Brun-Buisson, C
Infection risk and cost-effectiveness of commercial bags or glass bottles for total parenteral nutrition.


Crit. Care Med., 1996

Mimoz, O ; Pieroni, L ; Lawrence, C ; Edouard, A ; Costa, Y ; Samii, K & al
Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients.


Arch. Intern. Med., 1987

Brun-Buisson, C; Abroug, F; Legrand, P; Huet, Y; Larabi, S; Rapin, M.
Diagnosis of central venous catheter-related sepsis : critical level of quantitative tip cultures.


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JAMA, 2015

Derde, LP ; Cooper, BS ; Brun-Buisson, C
Contact precautions for patients with multidrug-resistant pathogens.


J. Antimicrob. Chemother., 2015

Izdebski, R ; Baraniak, A ; Herda, M ; Fiett, J ; Bonten, MJ ; Carmeli, Y & al
MLST reveals potentially high-risk international clones of Enterobacter cloacae.


J. Antimicrob. Chemother., 2015

Papagiannitsis, CC ; Izdebski, R ; Baraniak, A ; Fiett, J ; Herda, M ; Hrabák, J & al
Survey of metallo-β-lactamase-producing Enterobacteriaceae colonizing patients in European ICUs and rehabilitation units, 2008-11.


Euro Surveill., 2014

Fournier, S ; Monteil, C ; Lepainteur, M ; Richard, C ; Brun-Buisson, C ; Jarlier, V & al
Long-term control of carbapenemase-producing Enterobacteriaceae at the scale of a large French multihospital institution: a nine-year experience, France, 2004 to 2012.


Intensive Care Med, 2014

Haverkate, MR ; Derde, LP ; Brun-Buisson, C ; Bonten, MJ ; Bootsma, MC
Duration of colonization with antimicrobial-resistant bacteria after ICU discharge.


Lancet Infect Dis, 2014

Bonten, MJ ; Brun-Buisson, C ; Cooper, BS ; Derde, LP
Care bundles in intensive care units – authors’ reply.


Infect Control Hosp Epidemiol, 2014

Landelle, C ; Verachten, M ; Legrand, P ; Girou, E ; Barbut, F ; Brun-Buisson, C
Contamination of healthcare workers’ hands with Clostridium difficile spores after caring for patients with C. difficile infection.


Lancet Infect Dis, 2014

Derde, LP ; Cooper, BS ; Goossens, H ; Malhotra-Kumar, S ; Willems, RJ ; Gniadkowski, M & al
Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial.


Infect Control Hosp Epidemiol, 2014

Mekontso Dessap, A ; Jansen, C ; Boissier, F ; Razazi, K ; de Prost, N ; Michaud, G & al
Risk of cross transmission with point-of-care ultrasound system: effect of a glass-sealed control panel on microbial contamination.


Intensive Care Med, 2013

Brun-Buisson, C ; Razazi, K ; Derde, LP ; Bonten, MJ
Control of colonisation with extended-spectrum β-lactamase-producing bacteria: reply to Zandstra et al.


N. Engl. J. Med., 2013

Cooper, B ; Brun-Buisson, C ; Bonten, M
Daily chlorhexidine bathing and hospital-acquired infection.


Infect Control Hosp Epidemiol, 2013

Landelle, C ; Legrand, P ; Lesprit, P ; Cizeau, F ; Ducellier, D ; Gouot, C & al
Protracted outbreak of multidrug-resistant Acinetobacter baumannii after intercontinental transfer of colonized patients.


BMJ Open, 2013

Lee, AS ; Cooper, BS ; Malhotra-Kumar, S ; Chalfine, A ; Daikos, GL ; Fankhauser, C & al
Comparison of strategies to reduce meticillin-resistant Staphylococcus aureus rates in surgical patients: a controlled multicentre intervention trial.


Euro Surveill., 2012

Fournier, S ; Brossier, F ; Fortineau, N ; Gillaizeau, F ; Akpabie, A ; Aubry, A & al
Long-term control of vancomycin-resistant Enterococcus faecium at the scale of a large multihospital institution: a seven-year experience.


Antimicrob Resist Infect Control, 2012

Fournier, S ; Brun-Buisson, C ; Jarlier, V
Twenty years of antimicrobial resistance control programme in a regional multi hospital institution, with focus on emerging bacteria (VRE and CPE).


J Travel Med, 2012

Fournier, S ; Lepainteur, M ; Kassis-Chikhani, N ; Huang, M ; Brun-Buisson, C ; Jarlier, V
Link between carbapenemase-producing Enterobacteria carriage and cross-border exchanges: eight-year surveillance in a large French multihospitals institution.


Intensive Care Med, 2012

Oostdijk, EA ; Wittekamp, BH ; Brun-Buisson, C ; Bonten, MJ
Selective decontamination in European intensive care patients.


Intensive Care Med, 2012

Razazi, K ; Derde, LP ; Verachten, M ; Legrand, P ; Lesprit, P ; Brun-Buisson, C
Clinical impact and risk factors for colonization with extended-spectrum β-lactamase-producing bacteria in the intensive care unit.


J. Hosp. Infect., 2004

Girou, E ; Chai, SH ; Oppein, F ; Legrand, P ; Ducellier, D ; Cizeau, F & al
Misuse of gloves: the foundation for poor compliance with hand hygiene and potential for microbial transmission?


Intensive Care Med, 2003

Bonten, MJ ; Brun-Buisson, C ; Weinstein, RA
Selective decontamination of the digestive tract: to stimulate or stifle?


Infect Control Hosp Epidemiol, 2003

Bouam, S ; Girou, E ; Brun-Buisson, C ; Karadimas, H ; Lepage, E
An intranet-based automated system for the surveillance of nosocomial infections: prospective validation compared with physicians’ self-reports.


BMJ, 2002

Girou, E ; Loyeau, S ; Legrand, P ; Oppein, F ; Brun-Buisson, C
Efficacy of handrubbing with alcohol based solution versus standard handwashing with antiseptic soap: randomised clinical trial.


Infect Control Hosp Epidemiol, 2000

Girou, E ; Azar, J ; Wolkenstein, P ; Cizeau, F ; Brun-Buisson, C ; Roujeau, JC
Comparison of systematic versus selective screening for methicillin-resistant Staphylococcus aureus carriage in a high-risk dermatology ward.


Infect Control Hosp Epidemiol, 1999

Brun-Buisson, C; Hopital Propre Study Group
Methicillin-resistant Staphylococcus aureus in French hospitals: A 2-month survey in 43 hospitals, 1995.


JAMA, 1999

Chaix, C ; Durand-Zaleski, I ; Alberti, C ; Brun-Buisson, C
Control of endemic methicillin-resistant Staphylococcus aureus: a cost-benefit analysis in an intensive care unit.


Clin. Infect. Dis., 1998

Girou, E ; Pujade, G ; Legrand, P ; Cizeau, F ; Brun-Buisson, C
Selective screening of carriers for control of methicillin-resistant Staphylococcus aureus (MRSA) in high-risk hospital areas with a high level of endemic MRSA.


Intensive Care Med, 1996

Brun-Buisson, C
Practice guidelines for prevention of infection in European ICUs: a call for standards.


J. Antimicrob. Chemother., 1996

Lawrence, C ; Cosseron, M ; Mimoz, O ; Brun-Buisson, C ; Costa, Y ; Samii, K & al
Use of the coagulase gene typing method for detection of carriers of methicillin-resistant Staphylococcus aureus.


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Intensive Care Med, 2011

Ouanes, I ; Lyazidi, A ; Danin, PE ; Rana, N ; Di Bari, A ; Abroug, F & al
Mechanical influences on fluid leakage past the tracheal tube cuff in a benchtop model.


Crit. Care Med., 2009

Ouanes, I ; Misset, B ; Philippart, F ; Lyazidi, A ; Brochard, L,
Prevention of ventilation-associated pneumonia: The main target of PEEP might be the cuff of the tracheal tube.


J Crit Care, 2008

Wunderink, RG ; Brun-Buisson, C
Ventilator-associated pneumonia: Lessons learned from clinical trials.


ACP J. Club, 2007

Brun-Buisson, C
Use of different diagnostic methods for ventilator-associated pneumonia did not affect mortality or targeted antibiotic use.


BMJ, 2007

Brun-Buisson, C
Preventing ventilator associated pneumonia.


Intensive Care Med, 2006

Veinstein, A ; Brun-Buisson, C ; Derrode, N ; Alvarez, A ; Pinsard, M ; Robert, R & al
Validation of an algorithm based on direct examination of specimens in suspected ventilator-associated pneumonia.


Chest, 2005

Brun-Buisson, C ; Fartoukh, M ; Lechapt, E ; Honoré, S ; Zahar, JR ; Cerf, C & al
Contribution of blinded, protected quantitative specimens to the diagnostic and therapeutic management of ventilator-associated pneumonia.


Ann. Intern. Med., 2004

Dodek, P ; Keenan, S ; Cook, D ; Heyland, D ; Jacka, M ; Hand, L & al
Evidence-based clinical practice guideline for the prevention of ventilator-associated pneumonia.


Am. J. Respir. Crit. Care Med., 2005

Lacherade, JC ; Auburtin, M ; Cerf, C ; Van de Louw, A ; Soufir, L ; Rebufat, Y & al
Impact of humidification systems on ventilator-associated pneumonia: a randomized multicenter trial.


Am. J. Respir. Crit. Care Med., 2003

Fartoukh, M ; Maitre, B ; Honoré, S ; Cerf, C ; Zahar, JR ; Brun-Buisson, C
Diagnosing pneumonia during mechanical ventilation: the clinical pulmonary infection score revisited.


Minerva Anestesiol, 2002

Brun-Buisson, C
Optimizing therapeutic approaches in ventilator-associated pneumonia.


Crit. Care Med., 2002

Jean, D ; Maître, B ; Tankovic, J ; Meignan, M ; Adnot, S ; Brun-Buisson, C & al
Beneficial effects of nitric oxide inhalation on pulmonary bacterial clearance.


Crit. Care Med., 2002

Stephan, F ; Yang, K ; Tankovic, J ; Soussy, CJ ; Dhonneur, G ; Duvaldestin, P & al
Impairment of polymorphonuclear neutrophil functions precedes nosocomial infections in critically ill patients.


Am. J. Respir. Crit. Care Med., 1999

Heyland, DK ; Cook, DJ ; Griffith, L ; Keenan, SP ; Brun-Buisson, C
The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials Group.


JAMA, 1998

Cook, D ; De Jonghe, B ; Brochard, L ; Brun-Buisson, C
Influence of airway management on ventilator-associated pneumonia: evidence from randomized trials.



Ann. Intern. Med., 1998

Cook, DJ ; Walter, SD ; Cook, RJ ; Griffith, LE ; Guyatt, GH ; Leasa, D & al
Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients.


Am. J. Respir. Crit. Care Med., 1997

Delclaux, C ; Roupie, E ; Blot, F ; Brochard, L ; Lemaire, F ; Brun-Buisson, C
Lower respiratory tract colonization and infection during severe acute respiratory distress syndrome: incidence and diagnosis.


Crit. Care Med., 1997

Cook, DJ ; Hébert, PC ; Heyland, DK ; Guyatt, GH ; Brun-Buisson, C ; Marshall, JC & al
How to use an article on therapy or prevention: pneumonia prevention using subglottic secretion drainage.


New Horiz, 1996

Cook, DJ ; Hébert, PC ; Heyland, DK ; Guyatt, GH ; Brun-Buisson, C ; Marshall, JC & al
Could invasive diagnostic techniques for ventilator-associated pneumonia be associated with reduced antibiotic usage in the ICU?


Thorax, 1995

Brun-Buisson, C
Nosocomial pneumonia during mechanical ventilation: problems with diagnostic criteria.


Am. Rev. Respir. Dis., 1991

Pham, LA; Brun-Buisson, C; Legrand, P; Rauss, A; Verra, F; Brochard, L; Lemaire, F.
Diagnosis of nosocomial pneumonia in mechanically ventilated patients. Comparison of a plugged telescoping catheter with the protected specimem brush.


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J. Am. Acad. Dermatol., 2015

Hua, C ; Sbidian, E ; Hemery, F ; Decousser, JW ; Bosc, R ; Amathieu, R & al
Prognostic factors in necrotizing soft-tissue infections (NSTI): A cohort study.


Intensive Care Med, 2015

de Prost, N ; Sbidian, E ; Chosidow, O ; Brun-Buisson, C ; Amathieu, R
Management of necrotizing soft tissue infections in the intensive care unit: results of an international survey.


Ann Fr Anesth Reanim, 2014

de Prost, N ; Bosc, R ; Brun-Buisson, C ; Chosidow, O ; Decousser, JW ; Dhonneur, G & al
[Necrotizing fasciitis: results of a survey on management practices in French-speaking intensive care units].


Clin. Microbiol. Infect., 2005

Zahar, JR ; Goveia, J ; Lesprit, P ; Brun-Buisson, C
Severe soft tissue infections of the extremities in patients admitted to an intensive care unit.


Clin. Infect. Dis., 2002

Ben M’Rad, M ; Brun-Buisson, C
A case of necrotizing fasciitis due to Streptococcus pneumoniae following topical administration of nonsteroidal anti-inflammatory drugs.


Rev Prat, 2001

Zahar, JR ; Brun-Buisson, C
[Dermo-hypodermitis and necrotizing fasciitis].


Ann Dermatol Venereol, 2001

Brun-Buisson, C
[The therapeutic approach to necrotizing fasciitis].


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Crit Care, 2014

Pfister, R ; Kochanek, M ; Leygeber, T ; Brun-Buisson, C ; Cuquemelle, E ; Machado, MB & al
Procalcitonin for diagnosis of bacterial pneumonia in critically ill patients during 2009 H1N1 influenza pandemic: a prospective cohort study, systematic review and individual patient data meta-analysis.


Intensive Care Med, 2014

Depuydt, P ; Brun-Buisson, C
Healthcare-associated pneumonia: another nail in the coffin?


BMJ Case Rep, 2013

Gibelin, A ; de Prost, N ; Brun-Buisson, C
Lung abscess complicating pneumococcal pneumonia: a causal role of non-steroidal anti-inflammatory drugs?


Crit Care, 2012

Richard, JC ; Pham, T ; Brun-Buisson, C ; Reignier, J ; Mercat, A ; Beduneau, G & al
Interest of a simple on-line screening registry for measuring ICU burden related to an influenza pandemic.


Acad Emerg Med, 2012

Renaud, B ; Brun-Buisson, C ; Santin, A ; Coma, E ; Noyez, C ; Fine, MJ & al
Outcomes of early, late, and no admission to the intensive care unit for patients hospitalized with community-acquired pneumonia.


Intensive Care Med, 2011

Cuquemelle, E ; Soulis, F ; Villers, D ; Roche-Campo, F ; Ara Somohano, C ; Fartoukh, M & al
Can procalcitonin help identify associated bacterial infection in patients with severe influenza pneumonia? A multicentre study.


Crit Care, 2009

Renaud, B ; Labarère, J ; Coma, E ; Santin, A ; Hayon, J ; Gurgui, M & al
Risk stratification of early admission to the intensive care unit of patients with no major criteria of severe community-acquired pneumonia: development of an international prediction rule.


Crit. Care Med., 2009

Renaud, B ; Santin, A ; Coma, E ; Camus, N ; Van Pelt, D ; Hayon, J & al,
Association between timing of intensive care unit admission and outcomes for emergency department patients with community-acquired pneumonia.


Clin. Infect. Dis., 2007

Renaud, B ; Coma, E ; Labarere, J ; Hayon, J ; Roy, PM ; Boureaux, H & al
Routine use of the Pneumonia Severity Index for guiding the site-of-treatment decision of patients with pneumonia in the emergency department: a multicenter, prospective, observational, controlled cohort study.


Clin. Infect. Dis., 1999

Deforges, L ; Legrand, P ; Tankovic, J ; Brun-Buisson, C ; Lang, P ; Soussy, CJ
Case of false-positive results of the urinary antigen test for Legionella pneumophila.


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Clin. Microbiol. Infect., 2011

Mekontso Dessap, A ; Vivier, E ; Girou, E ; Brun-Buisson, C ; Kirsch, M,
Effect of time to onset on clinical features and prognosis of post-sternotomy mediastinitis.


J. Infect., 2009

Mekontso Dessap, A ; Zahar, JR ; Voiriot, G ; Ali, F ; Aissa, N ; Kirsch, M & al,
Influence of preoperative antibiotherapy on valve culture results and outcome of endocarditis requiring surgery.


Shock, 2005

Mekontso-Dessap, A ; Honoré, S ; Kirsch, M ; Plonquet, A ; Fernandez, E ; Touqui, L & al
Blood neutrophil bactericidal activity against methicillin-resistant and methicillin-sensitive Staphylococcus aureus during cardiac surgery.


J. Clin. Microbiol., 2004

Mekontso-Dessap, A ; Honoré, S ; Kirsch, M ; Houël, R ; Loisance, D ; Brun-Buisson, C
Usefulness of routine epicardial pacing wire culture for early prediction of poststernotomy mediastinitis.


Clin. Infect. Dis., 2002

Mekontso-Dessap, A ; Kirsch, M ; Vermes, E ; Brun-Buisson, C ; Loisance, D ; Houël, R
Nosocomial infections occurring during receipt of circulatory support with the paracorporeal ventricular assist system.


Ann. Thorac. Surg., 2001

Kirsch, M ; Mekontso-Dessap, A ; Houël, R ; Giroud, E ; Hillion, ML ; Loisance, DY
Closed drainage using redon catheters for poststernotomy mediastinitis: results and risk factors for adverse outcome.


Clin. Infect. Dis., 2001

Mekontso-Dessap, A ; Kirsch, M ; Brun-Buisson, C ; Loisance, D
Poststernotomy mediastinitis due to Staphylococcus aureus: comparison of methicillin-resistant and methicillin-susceptible cases.
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J. Clin. Microbiol., 2015

Contou, D ; Dacheux, L ; Bendib, I ; Jolivet, S ; Rodriguez, C ; Tomberli, F & al
Severe ketoalkalosis as initial presentation of imported human rabies in france.


Am. J. Respir. Crit. Care Med., 2015

Schortgen, F ; Asfar, P
Update in sepsis and acute kidney injury 2014.


Intensive Care Med, 2015

Schortgen, F ; Charles-Nelson, A ; Bouadma, L ; Bizouard, G ; Brochard, L ; Katsahian, S
Respective impact of lowering body temperature and heart rate on mortality in septic shock: mediation analysis of a randomized trial.


Med Mal Infect, 2014

Boissier, F ; Vermersch, C ; Spagnolo, S ; Bruneel, F ; Brun-Buisson, C ; de Prost, N
Septic shock complicating Plasmodium falciparum malaria in a pregnant patient with low parasitemia.


Intensive Care Med, 2014

Taccone, FS ; Saxena, M ; Schortgen, F
What’s new with fever control in the ICU.


Crit Care, 2013

de Prost, N ; Razazi, K ; Brun-Buisson, C
Unrevealing culture-negative severe sepsis.


Am. J. Respir. Crit. Care Med., 2013

Annane, D ; Timsit, JF ; Megarbane, B ; Martin, C ; Misset, B ; Mourvillier, B & al
Recombinant human activated protein C for adults with septic shock: a randomized controlled trial.


Ann. Intern. Med., 2012

Brun-Buisson, C
ACP Journal Club: drotrecogin alfa (activated) did not reduce mortality at 28 or 90 days in patients with septic shock.


Minerva Anestesiol, 2012

Schortgen, F
Fever in sepsis.


Am. J. Respir. Crit. Care Med., 2012

Schortgen, F ; Clabault, K ; Katsahian, S ; Devaquet, J ; Mercat, A ; Deye, N & al
Fever control using external cooling in septic shock: a randomized controlled trial.


Réanimation, 2011

A. Mekontso Dessap
Nouvelles pistes dans le traitement du sepsis — Place des statins


Crit Care, 2011

Mekontso Dessap, A ; Ouanes, I ; Rana, N ; Borghi, B ; Bazin, C ; Katsahian, S & al
Effects of discontinuing or continuing ongoing statin therapy in severe sepsis and septic shock: a retrospective cohort study.


Intensive Care Med, 2010

Bloos, F ; Hinder, F ; Becker, K ; Sachse, S ; Mekontso Dessap, A ; Straube, E & al
A multicenter trial to compare blood culture with polymerase chain reaction in severe human sepsis.


Intensive Care Med, 2008

Brun-Buisson, C
ICU-acquired infections and sepsis: more of a deadly duo.


Intensive Care Med, 2008

Dellinger, RP ; Levy, MM ; Carlet, JM ; Bion, J ; Parker, MM ; Jaeschke, R & al
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.


Intensive Care Med, 2006

Mekontso-Dessap, A ; Brun-Buisson, C
Statins: the next step in adjuvant therapy for sepsis?


Am. J. Respir. Crit. Care Med., 2005

Alberti, C ; Brun-Buisson, C ; Chevret, S ; Antonelli, M ; Goodman, SV ; Martin, C & al
Systemic inflammatory response and progression to severe sepsis in critically ill infected patients.


Crit. Care Med., 2004

Cohen, J ; Brun-Buisson, C ; Torres, A ; Jorgensen, J
Diagnosis of infection in sepsis: an evidence-based review.


Intensive Care Med, 2004

Brun-Buisson, C ; Meshaka, P ; Pinton, P ; Vallet, B
EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units.


Intensive Care Med, 2003

Brun-Buisson, C ; Roudot-Thoraval, F ; Girou, E ; Grenier-Sennelier, C ; Durand-Zaleski, I
The costs of septic syndromes in the intensive care unit and influence of hospital-acquired sepsis.


Am. J. Respir. Crit. Care Med., 2003

Alberti, C ; Brun-Buisson, C ; Goodman, SV ; Guidici, D ; Granton, J ; Moreno, R & al
Influence of systemic inflammatory response syndrome and sepsis on outcome of critically ill infected patients.


Intensive Care Med, 2002

Alberti, C ; Brun-Buisson, C ; Burchardi, H ; Martin, C ; Goodman, S ; Artigas, A & al
Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study.


Clin. Infect. Dis., 2001

Thiéry, G ; Tankovic, J ; Brun-Buisson, C ; Blot, F
Gonococcemia associated with fatal septic shock.


Intensive Care Med, 2000

Bion, JF ; Brun-Buisson, C
Introduction–infection and critical illness: genetic and environmental aspects of susceptibility and resistance.


JAMA, 1995

Brun-Buisson, C ; Doyon, F ; Carlet, J
Bacteremia and severe sepsis in adults: a multicenter prospective survey in ICUs and wards of 24 hospitals. French Bacteremia-Sepsis Study Group.


JAMA, 1995

Brun-Buisson, C ; Doyon, F ; Carlet, J ; Dellamonica, P ; Gouin, F ; Lepoutre, A & al
Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis.


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